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What DO we do?
What DO we do?
We study the type 2 immune response (immunocytes-TH2, ILC2, M2 macrophages; cytokines-IL-33, IL-4, IL-5, IL-13) and their role in tumor progression and autoimmune diseases and how we can leverage them as a potential drug target to treat diseases. We also study how the intratumor microbiome (bacteria and fungi) evokes type 2 immune response in cancers.
We study the type 2 immune response (immunocytes-TH2, ILC2, M2 macrophages; cytokines-IL-33, IL-4, IL-5, IL-13) and their role in tumor progression and autoimmune diseases and how we can leverage them as a potential drug target to treat diseases. We also study how the intratumor microbiome (bacteria and fungi) evokes type 2 immune response in cancers.
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Our Tools
We use genetically engineered mouse model (GEM) of the tumor, human and mouse organoid model, and human patient-derived xenograft (PDXs) along with functional genomics technology, metabolomic tracing, and multiplexed immune profiling.
We use genetically engineered mouse model (GEM) of the tumor, human and mouse organoid model, and human patient-derived xenograft (PDXs) along with functional genomics technology, metabolomic tracing, and multiplexed immune profiling.
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