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31. Pat Gulhati, Aislyn Schalck, Shan Jiang, Xiaoying Shang, Chang-Jiun Wu, Pingping Hou, Sharia Hernandez Ruiz, Luisa Solis Soto, Edwin Parra, Haoqiang Ying, Jincheng Han, Prasenjit Dey, Jun Li, Pingna Deng, Emi Sei, Dean Y Maeda, John A Zebala, Denise J Spring, Michael Kim, Huamin Wang, Anirban Maitra, Dirk Moore, Karen Clise-Dwyer, Y Alan Wang, Nicholas E Navin, Ronald A DePinho. Targeting T cell checkpoints 41BB and LAG3 and myeloid cell CXCR1/CXCR2 results in antitumor immunity and durable response in pancreatic cancer. Nature Cancer, 2023 Pubmed
30. Vishnu Kumarasamy, Costakis Frangou, Jianxin Wang, Yin Wan, Andrew Dynka, Hanna Rosenheck, Prasenjit Dey, Ethan V Abel, Erik S Knudsen, Agnieszka K Witkiewicz. Pharmacologically targeting KRASG12D in PDAC models: tumor cell intrinsic and extrinsic impact. bioRxiv, 2023. PDF
29. Spencer R Rosario, Bowen Dong, Yali Zhang, Hua-Hsin Hsiao, Emily Isenhart, Jianmin Wang, Erin M Siegel, Arta M Monjazeb, Dwight H Owen, Prasenjit Dey, Fred K Tabung, Daniel J Spakowicz, William J Murphy, Stephen Edge, Sai Yendamuri, Sami Ibrahimi, Jill M Kolesar, Patsy H McDonald, Deepak Vadehra, Michelle Churchman, Song Liu, Pawel Kalinski, Sarbajit Mukherjee. Metabolic Dysregulation Explains the Diverse Impacts of Obesity in Males and Females with Gastrointestinal Cancers. International Journal of Molecular Sciences, 2023 PDF
28. Taylor Mandeville, Cory Mavis, Juan Gu, Noah Lemoine, Kevin Bowman, Scott Olejniczak, Prasenjit Dey, Gyorgy Paragh, Francisco Hernandez-Ilizaliturri. Enhancing α-CD19 CAR T Antitumor Efficacy Using the BH3 Mimetic, Venetoclax. Blood, 2022. PDF
27. Aftab Alam, Sarah Comer, Eric Levanduski, Prasenjit Dey. Fungal ablation and transplantation of specific fungal species into PDAC tumor-bearing mice. STAR Protocol 2022 Aug 25 23;3(3):101644 Pubmed PDF
26. Peiwen Chen and Prasenjit Dey. Co-dependencies in the tumor immune microenvironment. Oncogene, July, 2022. Pubmed PDF
25. Aftab Alam, Sarah Comer, Eric Levanduski, Prasenjit Dey. Isolation and adoptive transfer of innate lymphoid cells 2 to a recipient mouse model of PDAC. STAR Protocol 2022 Jul 18;3(3):101563. Pubmed PDF
24. Aftab Alam, Eric Levanduski, Parker Denz, Helena Solleiro Villavicencio, Maulasri Bhatta, Lamees Alhorebi, Yali Zhang, Eduardo Cortes Gomez, Brian Morreale, Sharon Senchanthisai, Jun Li, Steven G. Turowski, Sandra Sexton, Sheila Jani Sait, Prashant K. Singh, Jianmin Wang, Anirban Maitra, Pawel Kalinski, Ronald A. DePinho, Huamin Wang, Wenting Liao, Scott I. Abrams, Brahm H. Segal, and Prasenjit Dey. Fungal mycobiome drives IL-33 secretion and type 2 immunity in pancreatic cancer. Cancer Cell, 2022, Pubmed PDF
23. Edoardo Del Poggetto, I-Lin Ho, Chiara Balestrieri, Er-Yen Yen, Shaojun Zhang, Francesca Citron, Rutvi Shah, Denise Corti, Giuseppe R Diaferia, Chieh-Yuan Li, Sara Loponte, Federica Carbone, Yoku Hayakawa, Giovanni Valenti, Shan Jiang, Luigi Sapio, Hong Jiang, Prasenjit Dey, Sisi Gao, Angela K Deem, Stefan Rose-John, Wantong Yao, Haoqiang Ying, Andrew D Rhim, Giannicola Genovese, Timothy P Heffernan, Anirban Maitra, Timothy C Wang, Linghua Wang, Giulio F Draetta, Alessandro Carugo, Gioacchino Natoli, Andrea Viale. Epithelial memory of inflammation limits tissue damage while promoting pancreatic tumorigenesis. Science, 2021, Pubmed PDF
22. Prasenjit Dey, Alec C. Kimmelman and Ronald A. DePinho. Metabolic Codependencies in the Tumor Microenvironment. Cancer Discovery. Online January 27, 2021, DOI: 10.1158/2159-8290.CD-20-1211. Pubmed PDF
21. Deepavali Chakravarti, Baoli Hu, Xizeng Mao, Asif Rashid, Jiexi Li, Jun Li, Wen-ting Liao, Elizabeth M Whitley, Prasenjit Dey, Pingping Hou, Kyle A LaBella, Andrew Chang, Guocan Wang, Denise J Spring, Pingna Deng, Di Zhao, Xin Liang, Zhengdao Lan, Yiyun Lin, Sharmistha Sarkar, Christopher Terranova, Yonathan Lissanu Deribe, Sarah E Blutt, Pablo Okhuysen, Jianhua Zhang, Eduardo Vilar, Ole Haagen Nielsen, Andrew Dupont, Mamoun Younes, Kalyani R Patel, Noah F Shroyer, Kunal Rai, Mary K Estes, Y Alan Wang, Alison A Bertuch, Ronald A DePinho. Telomere dysfunction activates YAP1 to drive tissue inflammation. Nature Communication. 2020 Sep 21;11(1):4766. doi: 10.1038/s41467-020-18420-w. PUBMED PDF
20. Pushan Dasgupta, Joy Gumin, Piergiorgio Pettazzoni, Floris Barthel, Angela Deem, Prasenjit Dey, Emmet Huang-Hobbs, Erik Sulman, Roel Verhaak, Frederick Lang, Giulio Draetta. IN VIVO FUNCTIONAL GENOMIC SCREEN IDENTIFIES WISP1 AS AN OVEREXPRESSED DRIVER OF GLIOBLASTOMA. Neuro-Oncology, Volume 22, Issue Supplement_2, November 2020, Page ii71. Neuro Oncology. PDF
19. Prasenjit Dey, Jun Li, Jianhua Zhang, Surendra Chaurasiya, Anders Strom, Huamin Wang, Wen-Ting Liao, Frederick Cavallaro, Parker Denz, Vincent Bernard, Er-Yen Yen, Giannicola Genovese, Pat Gulhati, Jielin Liu, Deepavali Chakravarti, Pingna Deng, Tingxin Zhang, Federica Carbone, Qing Chang, Haoqiang Ying, Xiaoying Shang, Denise J. Spring, Bidyut Ghosh, Nagireddy Putluri, Anirban Maitra, Y. Alan Wang and Ronald A. DePinho. Oncogenic Kras driven metabolic reprogramming in pancreas cancer cells utilizes cytokines from the tumor microenvironment. Cancer Discovery. Online February 11, 2020, doi: 10.1158/2159-8290.CD-19-0297 Pubmed PDF
18. Liao WT, Boutin A, Dey P, Wang G, Zhao D, Lan Z, Li J, Li J, Shang X, Tang M, Jiang S, Ma X, Chen P, Katkhuda R, Korphaisarn K, Chang A, Overman MJ, Spring DJ, Maeda DY, Zebala JA, Zhang J, Maru DM, Kopetz S, Wang YA, and DePinho RA. KRAS-IRF2 axis drives immune suppression and immune therapy resistance in colorectal cancer. Cancer Cell 2019 March doi.org/10.1016/j.ccell.2019.02.008. Pubmed PDF
17. Carugo A, Minelli R, Sapio L, Soeung M, Chen Z, Carbone F, Robinson F, Tepper J, Lovisa S, Amin S, Srinivasan S, Poggetto ED, Lopont S, Puca F, Dey P, Malouf G, Su X, Lopez-Terrada D, Rakheja D, Lazar A, Netto G, Rao P, Sgambato A, Maitra A, Tripathi D, Walker C, Karam J, Msaouel P, Heffernan T, Viale A, Roberts C, Tannir N, Draetta G, and Genovese G. TP53 is a master regulator of proteostasis in SMARCB1 deficient tumors. Cancer Cell 2019 Feb 11;35(2):204-220.e9. doi: 10.1016/j.ccell.2019.01.006 Pubmed PDF
16. Faria M, Karami S, Granados-Principal S, Dey P, Verma A, Choi D, Olivier Elemento, Bawa-Khalfe T, Chang J, Strom A, Gustafsson JA. The ERβ4 variant induces Transformation of the Normal Breast Mammary Epithelial cell line MCF-10A; the ERβ variants ERβ2 and ERβ5 increase aggressiveness of TNBC by regulation of hypoxic signaling. Oncotarget January 2018, DOI 10.18632/oncotarget.24134 Pubmed PDF
15. Sarkar S, Bristow C, Dey P, Rai K, Perets R, Cardenas-Ramirez A, Malasi S, Huang-Hobbs E, Haemmerle M, Wu S, McGuire M, Propopotov A, Jiang S, Garvey J, Liu J, Hirsch M, Chang Q, Lazar A, Sood A, Drapkin R, Depinho RA, Draetta G. PRKCI promotes immune suppression in ovarian tumors through YAP1. Genes and Development July 2017, doi:10.1101/gad.296640.117. Pubmed PDF
14. Genovese G, Carugo A, Tepper J, Robinson FS, Li L, Svelto M, Nezi L, Corti D, Minelli R, Pettazzoni P, Gutschner T, Wu CC, Seth S, Akdemir KC, Leo E, Amin S, Molin MD, Ying H, Kwong LN, Colla S, Takahashi K, Ghosh P, Giuliani V, Muller F, Dey P, Jiang S, Garvey J, Liu CG, Zhang J, Heffernan TP, Toniatti C, Fleming JB, Goggins MG, Wood LD, Sgambato A, Agaimy A, Maitra A, Roberts CW, Wang H, Viale A, DePinho RA, Draetta GF, Chin L. Synthetic vulnerabilities of mesenchymal subpopulations in pancreatic cancer. Nature 542(7641): 362-366 (2017) doi: 10.1038/nature21064. Pubmed PDF
13. Zhao D, Lu X, Wang G, Lan Z, Liao W, Li J, Liang X, Chen JR, Shah S, Shang X, Tang M, Deng P, Dey P, Chakravarti D, Chen P, Spring DJ, Navone NM, Troncoso P, Zhang J, Wang YA, DePinho RA. Synthetic essentiality of chromatin remodeling factor CHD1 in PTEN deficient cancer. Nature 542: 484-488 (2017) doi:10.1038/nature21357. Pubmed PDF
12. Dey P, Baddour J, Muller F, Wu CC, Wang H, Liao WT, Lan Z, Chen A, Gutschner T, Kang Y, Fleming J, Satani N, Zhao D, Achreja A, Yang L, Lee J, Chang E, Genovese G, Viale A, Ying H, Draetta G, Maitra A, Wang YA, Nagrath D, DePinho RA. Genomic deletion of malic enzyme 2 confers collateral lethality in pancreatic cancer. Nature 542: 119–123 (2017) doi:10.1038/nature21052. Pubmed PDF
11. Wang G, Lu X, Dey P#, Deng P, Wu CC, Jiang S, Fang Z, Zhao K, Konaparthi R, Hua S, Zhang J, Li-Ning-Tapia EM, Kapoor A, Wu CJ, Patel NB, Guo Z, Ramamoorthy V, Tieu TN, Heffernan T, Zhao D, Shang X, Khadka S, Hou P, Hu B, Jin EJ, Yao W, Pan X, Ding Z, Shi Y, Li L, Chang Q, Troncoso P, Logothetis CJ, McArthur MJ, Chin L, Wang YA, DePinho RA. Targeting YAP-dependent MDSC infiltration impairs tumor progression. Cancer Discovery 6(1): 80–95 (2016) doi: 10.1158/2159-8290.CD-15-0224. Pubmed PDF
10. Ying H, Dey P, Yao W, Kimmelman AC, Draetta GF, Maitra A, DePinho RA. Genetics and biology of pancreatic ductal adenocarcinoma. Genes & Development 30(4):355-385 (2016) doi: 10.1101/gad.275776.115. Pubmed PDF
9. Storer Samaniego C, Suh JH, Chattopadhyay A, Olivares K, Guy N, Sivils JC, Dey P, Yumoto F, Fletterick RJ, Strom AM, Gustafsson JÅ, Webb P, Cox MB. The 52-kDa FK506-Binding Protein (FKBP52) Acts in Synergy with β-Catenin to Potentiate Androgen Receptor Signaling. PLOS One 10: e0134015 (2015) doi: 10.1371/journal.pone.0134015. Pubmed PDF
8. Dey P, Velazquez-Villegas LA, Faria M, Turner A, Jonsson P, Webb P, Williams C, Gustafsson JÅ, Ström AM. Estrogen receptor β2 induces hypoxia signature of gene expression by stabilizing HIF-1α in prostate cancer. PloS One 10(5): e0128239-e0128239 (2015) doi: 10.1371/journal.pone.0128239. Pubmed PDF
7. Candelaria NR, Addanki S, Zheng J, Nguyen-Vu T, Karaboga H, Dey P, Gabbi C, Vedin LL, Liu K, Wu W, Jonsson PK, Lin JZ, Su F, Bollu LR, Hodges SE, McElhany AL, Issazadeh MA, Fisher WE, Ittmann MM, Steffensen KR, Gustafsson JÅ, Lin CY. Antiproliferative Effects and Mechanisms of Liver X Receptor Ligands in Pancreatic Ductal Adenocarcinoma Cells. Plos One 9(9): e106289 (2014) doi: 10.1371/journal.pone.0106289. Pubmed PDF
6. Dey P, Ström A, Gustafsson JÅ. Estrogen receptor β upregulates FOXO3a and causes induction of apoptosis through PUMA in prostate cancer. Oncogene 33(33): 4213-4225 (2014) doi: 10.1038/onc.2013.384. Pubmed PDF
5. Dey P, Barros RP, Warner M, Ström A, Gustafsson JÅ. Insight into the mechanisms of action of estrogen receptor beta in the breast, prostate, colon and CNS. Journal of Molecular Endocrinology 51(3): T61-74 (2013) doi: 10.1530/JME-13-0150. Pubmed PDF
4. Dey P, Jonsson P, Hartman J, Williams C, Ström A, Gustafsson JÅ. Estrogen receptors b1 and b2 have opposing roles in regulating proliferation and bone metastasis genes in the prostate cancer cell line PC3. Molecular Endocrinology 26(12): 1991-2003 (2012) doi: 10.1210/me.2012.1227. Pubmed PDF
3. Liu Y, Stepanov V, Dey P, Jackson GW, Willson RC, Fox GE. System for large-scale production of small RNAs through their in vivo expression within 5S rRNA-derived scaffold. FASEB J. April 2009, 23 (Meeting Abstract Supplement) 846.5.
2. Dey P, Gupta P, Acharya NK, Rao SN, Ray S, Chakrabarty S, Ramprasad S, Kurian TA, Mawroh A, Kundu A, Bhaktha G, Joseph CP, Kumar P, Rai L, Rao A. Antioxidants and Lipid peroxidation in Gestational Diabetes Mellitus-A preliminary study. Indian Journal of Physiology and Pharmacology 52(2): 149-156 (2008).
